Abstract
Hydrogen bromide has been demonstrated to provide optimal cis-selectivity in the reduction of 4-chromanone α-hydroxyoxime (25:1 cis/trans) in 94% yield. This reaction is pivotal in the synthesis of cis-aminochromanol. (C) 2000 Elsevier Science Ltd.
Original language | English (US) |
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Pages (from-to) | 8021-8025 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 41 |
Issue number | 42 |
DOIs | |
State | Published - Oct 14 2000 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry