Stem cell fusion in the brain

Yevgenia Kozorovitskiy, Elizabeth Gould

Research output: Contribution to journalComment/debate

23 Scopus citations

Abstract

Bone-marrow-derived stem cells have been shown to contribute to Purkinje neurons in the cerebellum of adult humans and mice. A new study identifies cell fusion as the mechanism underlying this phenomenon, and shows that the bone marrow cell portion of the resulting binucleate heterokaryons acquires the morphological and molecular characteristics of Purkinje neurons over time.

Original languageEnglish (US)
Pages (from-to)952-954
Number of pages3
JournalNature Cell Biology
Volume5
Issue number11
DOIs
StatePublished - Nov 1 2003

All Science Journal Classification (ASJC) codes

  • Cell Biology

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