Stem cell fusion in the brain

Yevgenia Kozorovitskiy; Elizabeth Gould

doi:10.1038/ncb1103-952

Stem cell fusion in the brain

Yevgenia Kozorovitskiy, Elizabeth Gould

Research output: Contribution to journal › Comment/debate › peer-review

26 Scopus citations

Abstract

Bone-marrow-derived stem cells have been shown to contribute to Purkinje neurons in the cerebellum of adult humans and mice. A new study identifies cell fusion as the mechanism underlying this phenomenon, and shows that the bone marrow cell portion of the resulting binucleate heterokaryons acquires the morphological and molecular characteristics of Purkinje neurons over time.

Original language	English (US)
Pages (from-to)	952-954
Number of pages	3
Journal	Nature cell biology
Volume	5
Issue number	11
DOIs	https://doi.org/10.1038/ncb1103-952
State	Published - Nov 2003

All Science Journal Classification (ASJC) codes

Cell Biology

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10.1038/ncb1103-952

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title = "Stem cell fusion in the brain",

abstract = "Bone-marrow-derived stem cells have been shown to contribute to Purkinje neurons in the cerebellum of adult humans and mice. A new study identifies cell fusion as the mechanism underlying this phenomenon, and shows that the bone marrow cell portion of the resulting binucleate heterokaryons acquires the morphological and molecular characteristics of Purkinje neurons over time.",

author = "Yevgenia Kozorovitskiy and Elizabeth Gould",

year = "2003",

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AB - Bone-marrow-derived stem cells have been shown to contribute to Purkinje neurons in the cerebellum of adult humans and mice. A new study identifies cell fusion as the mechanism underlying this phenomenon, and shows that the bone marrow cell portion of the resulting binucleate heterokaryons acquires the morphological and molecular characteristics of Purkinje neurons over time.

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DO - 10.1038/ncb1103-952

M3 - Comment/debate

C2 - 14593417

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SP - 952

EP - 954

JO - Nature cell biology

JF - Nature cell biology

IS - 11

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Stem cell fusion in the brain

Abstract

All Science Journal Classification (ASJC) codes

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