Statics and dynamics of single DNA molecules confined in nanochannels

Walter Reisner; Keith J. Morton; Robert Riehn; Yan Mei Wang; Zhaoning Yu; Michael Rosen; James C. Sturm; Stephen Y. Chou; Erwin Frey; Robert H. Austin

doi:10.1103/PhysRevLett.94.196101

Statics and dynamics of single DNA molecules confined in nanochannels

Walter Reisner, Keith J. Morton, Robert Riehn, Yan Mei Wang, Zhaoning Yu, Michael Rosen, James C. Sturm, Stephen Y. Chou, Erwin Frey, Robert H. Austin

Research output: Contribution to journal › Article › peer-review

494 Scopus citations

Abstract

The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.

Original language	English (US)
Article number	196101
Journal	Physical review letters
Volume	94
Issue number	19
DOIs	https://doi.org/10.1103/PhysRevLett.94.196101
State	Published - May 20 2005

All Science Journal Classification (ASJC) codes

General Physics and Astronomy

Access to Document

10.1103/PhysRevLett.94.196101

Cite this

@article{a7fc07c076b648bdb05f0dadd5465dd2,

title = "Statics and dynamics of single DNA molecules confined in nanochannels",

abstract = "The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.",

author = "Walter Reisner and Morton, {Keith J.} and Robert Riehn and Wang, {Yan Mei} and Zhaoning Yu and Michael Rosen and Sturm, {James C.} and Chou, {Stephen Y.} and Erwin Frey and Austin, {Robert H.}",

year = "2005",

month = may,

day = "20",

doi = "10.1103/PhysRevLett.94.196101",

language = "English (US)",

volume = "94",

journal = "Physical review letters",

issn = "0031-9007",

publisher = "American Physical Society",

number = "19",

}

TY - JOUR

T1 - Statics and dynamics of single DNA molecules confined in nanochannels

AU - Reisner, Walter

AU - Morton, Keith J.

AU - Riehn, Robert

AU - Wang, Yan Mei

AU - Yu, Zhaoning

AU - Rosen, Michael

AU - Sturm, James C.

AU - Chou, Stephen Y.

AU - Frey, Erwin

AU - Austin, Robert H.

PY - 2005/5/20

Y1 - 2005/5/20

N2 - The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.

AB - The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.

UR - http://www.scopus.com/inward/record.url?scp=22544464468&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=22544464468&partnerID=8YFLogxK

U2 - 10.1103/PhysRevLett.94.196101

DO - 10.1103/PhysRevLett.94.196101

M3 - Article

C2 - 16090189

AN - SCOPUS:22544464468

SN - 0031-9007

VL - 94

JO - Physical review letters

JF - Physical review letters

IS - 19

M1 - 196101

ER -

Statics and dynamics of single DNA molecules confined in nanochannels

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this