Spike-triggered neural characterization

Odelia Schwartz, Jonathan W. Pillow, Nicole C. Rust, Eero P. Simoncelli

Research output: Contribution to journalArticle

251 Scopus citations

Abstract

Response properties of sensory neurons are commonly described using receptive fields. This description may be formalized in a model that operates with a small set of linear filters whose outputs are nonlinearly combined to determine the instantaneous firing rate. Spike-triggered average and covariance analyses can be used to estimate the filters and nonlinear combination rule from extracellular experimental data. We describe this methodology, demonstrating it with simulated model neuron examples that emphasize practical issues that arise in experimental situations.

Original languageEnglish (US)
Article number13
Pages (from-to)484-507
Number of pages24
JournalJournal of vision
Volume6
Issue number4
DOIs
StatePublished - Jul 17 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems

Keywords

  • Characterization
  • Neural response
  • Nonlinear
  • Receptive field
  • Reverse correlation
  • Spike-triggered analysis

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  • Cite this

    Schwartz, O., Pillow, J. W., Rust, N. C., & Simoncelli, E. P. (2006). Spike-triggered neural characterization. Journal of vision, 6(4), 484-507. [13]. https://doi.org/10.1167/6.4.13