Spike Timing in the Attention Network Predicts Behavioral Outcome Prior to Target Selection

Ian C. Fiebelkorn, Sabine Kastner

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


There has been little evidence linking changes in spiking activity that occur prior to a spatially predictable target (i.e., prior to target selection) to behavioral outcomes, despite such preparatory changes being widely assumed to enhance the sensitivity of sensory processing. We simultaneously recorded from frontal and parietal nodes of the attention network while macaques performed a spatial cueing task. When anticipating a spatially predictable target, different patterns of coupling between spike timing and the oscillatory phase in local field potentials—but not changes in spike rate—were predictive of different behavioral outcomes. These behaviorally relevant differences in local and between-region synchronization occurred among specific cell types that were defined based on their sensory and motor properties, providing insight into the mechanisms underlying enhanced sensory processing prior to target selection. We propose that these changes in neural synchronization reflect differential anticipatory engagement of the network nodes and functional units that shape attention-related sampling.

Original languageEnglish (US)
Pages (from-to)177-188.e4
Issue number1
StatePublished - Jan 6 2021

All Science Journal Classification (ASJC) codes

  • General Neuroscience


  • FEF
  • LIP
  • attention
  • neurophysiology
  • oscillations
  • spike timing
  • vision


Dive into the research topics of 'Spike Timing in the Attention Network Predicts Behavioral Outcome Prior to Target Selection'. Together they form a unique fingerprint.

Cite this