Abstract
Fluoroarene-Cr(CO)2L complexes with L = CO, PPh3, P(OPh)3, P(pyrrolyl)3, and P(pyrrolyl)2(NMeBn) have been evaluated for rates of nucleophilic substitution by amines and other nucleophiles. While there is a strong effect on relative rates depending on nucleophile type and the electronic effects of L, the P(pyrrolyl)3 and P(pyrrolyl)2-(NMeBn) complexes show general reactivity comparable to the parent complexes, with L = CO.
Original language | English (US) |
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Pages (from-to) | 7683-7686 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 39 |
Issue number | 42 |
DOIs | |
State | Published - Oct 15 1998 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry
Keywords
- Fluoroarene-chromium
- Nucleophilic substitution
- P(pyrrolyl)
- S(N)Ar