Six challenges in the eradication of infectious diseases

Petra Klepac, Sebastian Funk, T. Deirdre Hollingsworth, C. Jessica E. Metcalf, Katie Hampson

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Eradication and elimination are increasingly a part of the global health agenda. Once control measures have driven infection to low levels, the ecology of disease may change posing challenges for eradication efforts. These challenges vary from identifying pockets of susceptibles, improving monitoring during and after the endgame, to quantifying the economics of disease eradication versus sustained control, all of which are shaped and influenced by processes of loss of immunity, susceptible build-up, emergence of resistance, population heterogeneities and non-compliance with control measures. Here we discuss how modelling can be used to address these challenges.

Original languageEnglish (US)
Pages (from-to)97-101
Number of pages5
StatePublished - Mar 2015

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Epidemiology
  • Virology
  • Parasitology
  • Microbiology


  • Dynamics
  • Elimination
  • Heterogeneity
  • Modelling
  • Surveillance


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