Simple and efficient resolution of l,1′-bi-2-naphthol

Dongwei Cai; David L. Hughes; Thomas R. Verhoeven; Paul J. Reider

doi:10.1016/0040-4039(95)01722-T

Simple and efficient resolution of l,1′-bi-2-naphthol

Dongwei Cai
, David L. Hughes
, Thomas R. Verhoeven
, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

168 Scopus citations

Abstract

Acetonitrile is a crucial solvent for a simple and efficient resolution of l,l′-bi-2-naphthol using N-benzylcincbonidium chloride. Both enantiomers can be easily obtained with ≥95% yield and ≥99% ee.

Original language	English (US)
Pages (from-to)	7991-7994
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	44
DOIs	https://doi.org/10.1016/0040-4039(95)01722-T
State	Published - Oct 30 1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(95)01722-T

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@article{03e0a59d0d7e4d0299ede416dbefa74e,

title = "Simple and efficient resolution of l,1′-bi-2-naphthol",

abstract = "Acetonitrile is a crucial solvent for a simple and efficient resolution of l,l′-bi-2-naphthol using N-benzylcincbonidium chloride. Both enantiomers can be easily obtained with ≥95\% yield and ≥99\% ee.",

author = "Dongwei Cai and Hughes, \{David L.\} and Verhoeven, \{Thomas R.\} and Reider, \{Paul J.\}",

year = "1995",

month = oct,

day = "30",

doi = "10.1016/0040-4039(95)01722-T",

language = "English (US)",

volume = "36",

pages = "7991--7994",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "44",

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TY - JOUR

T1 - Simple and efficient resolution of l,1′-bi-2-naphthol

AU - Cai, Dongwei

AU - Hughes, David L.

AU - Verhoeven, Thomas R.

AU - Reider, Paul J.

PY - 1995/10/30

Y1 - 1995/10/30

N2 - Acetonitrile is a crucial solvent for a simple and efficient resolution of l,l′-bi-2-naphthol using N-benzylcincbonidium chloride. Both enantiomers can be easily obtained with ≥95% yield and ≥99% ee.

AB - Acetonitrile is a crucial solvent for a simple and efficient resolution of l,l′-bi-2-naphthol using N-benzylcincbonidium chloride. Both enantiomers can be easily obtained with ≥95% yield and ≥99% ee.

UR - https://www.scopus.com/pages/publications/0028808574

UR - https://www.scopus.com/pages/publications/0028808574#tab=citedBy

U2 - 10.1016/0040-4039(95)01722-T

DO - 10.1016/0040-4039(95)01722-T

M3 - Article

AN - SCOPUS:0028808574

SN - 0040-4039

VL - 36

SP - 7991

EP - 7994

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 44

ER -

Simple and efficient resolution of l,1′-bi-2-naphthol

Abstract

All Science Journal Classification (ASJC) codes

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