Signal transduction: Ggyrating protein kinases

Research output: Contribution to journalComment/debatepeer-review

30 Scopus citations


Recently determined structures have linked histidine kinases with class II topoisomerases, the DNA repair enzyme MutL and the molecular chaperone Hsp90. This surprising finding may foreshadow a shift in our understanding of energy coupling mechanisms in signal transduction networks.

Original languageEnglish (US)
Pages (from-to)R364-R367
JournalCurrent Biology
Issue number10
StatePublished - May 20 1999

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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