Serotonin and motor activity

Barry L. Jacobs, Casimir A. Fornal

Research output: Contribution to journalArticle

225 Scopus citations

Abstract

The activity of brain serotonergic neurons in both the pontine-mesencephalic and medullary groups is positively correlated with the level of behavioral arousal and/or the behavioral state. This, in turn, appears to be related to the level of tonic motor activity, especially as manifested in antigravity muscles and other muscle groups associated with gross motor activity. In addition, a subset of serotonergic neurons displays a further increase in activity in association with repetitive, central pattern generator mediated responses. Accumulating evidence indicates that this relation to motor activity is related both to the co-activation of the sympathetic nervous system and to the modulation of afferent inputs.

Original languageEnglish (US)
Pages (from-to)820-825
Number of pages6
JournalCurrent Opinion in Neurobiology
Volume7
Issue number6
DOIs
StatePublished - Dec 1997

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Serotonin and motor activity'. Together they form a unique fingerprint.

  • Cite this