Abstract
Serotonin, like dopamine (DA), has long been implicated in adaptive behavior, including decision making and reinforcement learning. However, although the two neuromodulators are tightly related and have a similar degree of functional importance, compared with DA, we have a much less specific understanding about the mechanisms by which serotonin affects behavior. Here, we draw on recent work on computational models of dopaminergic function to suggest a framework by which many of the seemingly diverse functions associated with both DA and serotoninFcomprising both affective and activational ones, as well as a number of other functions not overtly related to eitherFcan be seen as consequences of a single root mechanism.
Original language | English (US) |
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Pages (from-to) | 98-113 |
Number of pages | 16 |
Journal | Neuropsychopharmacology |
Volume | 36 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2011 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Psychiatry and Mental health
- Pharmacology
Keywords
- activation
- aversion
- impulsivity
- inhibition
- punishment
- reward