Serotonin and behavior: Emphasis on motor control

B. L. Jacobs

Research output: Contribution to journalReview articlepeer-review

82 Scopus citations


Electrophysiologic studies of brain serotonergic neurons in behaving animals indicate that their activity is closely related to the sleep-wake-arousal cycle and to certain specific types of repetitive motor activity. A variety of other environmental and physiologic manipulations are ineffective in altering the activity of this neurochemical system. An attempt is made to relate these results to well-known involvement of brain serotonin in human affective disorders.

Original languageEnglish (US)
Pages (from-to)17-23
Number of pages7
JournalJournal of Clinical Psychiatry
Issue number12 SUPPL.
StatePublished - 1991

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health


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