Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein

Scott D. Emr, Joe Hedgpeth, Jean Marie Clément, Thomas J. Silhavy, Maurice Hofnung

Research output: Contribution to journalArticlepeer-review

96 Scopus citations

Abstract

The ammo-terminal signal sequence is required for initiation of transmembrane protein transfer of the Escherichia coli λ receptor protein. Mutations leading to insertion of charged amino acids into or deletion of amino acids from the hydrophobic segment of this sequence prevent export of this outer membrane protein.

Original languageEnglish (US)
Pages (from-to)82-85
Number of pages4
JournalNature
Volume285
Issue number5760
DOIs
StatePublished - Dec 1 1980
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General

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