Sensory transduction in bacterial chemotaxis involves phosphotransfer between CHE proteins

David Wylie, Ann Stock, Cing Yuen Wong, Jeff Stock

Research output: Contribution to journalArticlepeer-review

131 Scopus citations

Abstract

The CheA protein of the Salmonella typhimurium chemotaxis system is phosphorylated by ATP. Phospho-CheA transfers its phosphoryl group to a second chemotaxis protein, CheY. Unlike phospho-CheA, phospho-CheY is relatively unstable, rapidly decaying to phosphate and CheY. We propose that phosphorylation of CheY may play a role in its function as a tumble regulator to control motor behavior in response to attractant and repellent stimuli.

Original languageEnglish (US)
Pages (from-to)891-896
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume151
Issue number2
DOIs
StatePublished - Mar 15 1988

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Biophysics
  • Biochemistry
  • Cell Biology

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