Self-sorting of white blood cells in a lattice

Robert H. Carlson; Christopher V. Gabel; Shirley S. Chan; Robert H. Austin; James P. Brody; James W. Winkelman

doi:10.1103/PhysRevLett.79.2149

Self-sorting of white blood cells in a lattice

Robert H. Carlson, Christopher V. Gabel, Shirley S. Chan, Robert H. Austin, James P. Brody, James W. Winkelman

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Abstract

When a drop of human blood containing red and white blood cells is forced to move via hydrodynamic forces in a lattice of channels designed to mimic the capillary channels, the white cells self-fractionate into the different types of white cells. The pattern of white cells that forms is due to a combination of stretch-activated adhesion of cells with the walls, stochastic sticking probabilities, and heteroavoidance between granulocytes and lymphocytes.

Original language	English (US)
Pages (from-to)	2149-2152
Number of pages	4
Journal	Physical review letters
Volume	79
Issue number	11
DOIs	https://doi.org/10.1103/PhysRevLett.79.2149
State	Published - Sep 15 1997

All Science Journal Classification (ASJC) codes

General Physics and Astronomy

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10.1103/PhysRevLett.79.2149

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abstract = "When a drop of human blood containing red and white blood cells is forced to move via hydrodynamic forces in a lattice of channels designed to mimic the capillary channels, the white cells self-fractionate into the different types of white cells. The pattern of white cells that forms is due to a combination of stretch-activated adhesion of cells with the walls, stochastic sticking probabilities, and heteroavoidance between granulocytes and lymphocytes.",

author = "Carlson, \{Robert H.\} and Gabel, \{Christopher V.\} and Chan, \{Shirley S.\} and Austin, \{Robert H.\} and Brody, \{James P.\} and Winkelman, \{James W.\}",

year = "1997",

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doi = "10.1103/PhysRevLett.79.2149",

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T1 - Self-sorting of white blood cells in a lattice

AU - Carlson, Robert H.

AU - Gabel, Christopher V.

AU - Chan, Shirley S.

AU - Austin, Robert H.

AU - Brody, James P.

AU - Winkelman, James W.

PY - 1997/9/15

Y1 - 1997/9/15

N2 - When a drop of human blood containing red and white blood cells is forced to move via hydrodynamic forces in a lattice of channels designed to mimic the capillary channels, the white cells self-fractionate into the different types of white cells. The pattern of white cells that forms is due to a combination of stretch-activated adhesion of cells with the walls, stochastic sticking probabilities, and heteroavoidance between granulocytes and lymphocytes.

AB - When a drop of human blood containing red and white blood cells is forced to move via hydrodynamic forces in a lattice of channels designed to mimic the capillary channels, the white cells self-fractionate into the different types of white cells. The pattern of white cells that forms is due to a combination of stretch-activated adhesion of cells with the walls, stochastic sticking probabilities, and heteroavoidance between granulocytes and lymphocytes.

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U2 - 10.1103/PhysRevLett.79.2149

DO - 10.1103/PhysRevLett.79.2149

M3 - Article

AN - SCOPUS:0001336954

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JO - Physical review letters

JF - Physical review letters

IS - 11

ER -

Self-sorting of white blood cells in a lattice

Abstract

All Science Journal Classification (ASJC) codes

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