Self-organized periodicity of protein clusters in growing bacteria

Hui Wang, Ned S. Wingreen, Ranjan Mukhopadhyay

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using fluorescence imaging have shown that, during cell growth, lateral clusters form at positions approximately periodically spaced along the cell body. In this Letter, we demonstrate within a lattice model that such spatial organization could arise spontaneously from a stochastic nucleation mechanism. The same mechanism may explain the recent observation of periodic aggregates of misfolded proteins in E. coli.

Original languageEnglish (US)
Article number218101
JournalPhysical review letters
Issue number21
StatePublished - Nov 20 2008

All Science Journal Classification (ASJC) codes

  • General Physics and Astronomy


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