Selection plays the hand it was dealt: Evidence that human adaptation commonly targets standing genetic variation

Rajiv C. McCoy; Joshua M. Akey

doi:10.1186/s13059-017-1280-5

Selection plays the hand it was dealt: Evidence that human adaptation commonly targets standing genetic variation

Rajiv C. McCoy, Joshua M. Akey

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Using a powerful machine learning approach, a recent study of human genomes has revealed widespread footprints of recent positive selection on standing genetic variation.

Original language	English (US)
Article number	139
Journal	Genome biology
Volume	18
Issue number	1
DOIs	https://doi.org/10.1186/s13059-017-1280-5
State	Published - Aug 1 2017
Externally published	Yes

All Science Journal Classification (ASJC) codes

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/s13059-017-1280-5

Cite this

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title = "Selection plays the hand it was dealt: Evidence that human adaptation commonly targets standing genetic variation",

abstract = "Using a powerful machine learning approach, a recent study of human genomes has revealed widespread footprints of recent positive selection on standing genetic variation.",

author = "McCoy, {Rajiv C.} and Akey, {Joshua M.}",

note = "Funding Information: RCM is supported by NIH/NHGRI training grant 5T32HG000035-22 to the University of Washington. This work is also partially supported by NIH grant R01GM110068 to JMA. Publisher Copyright: {\textcopyright} 2017 The Author(s).",

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Selection plays the hand it was dealt: Evidence that human adaptation commonly targets standing genetic variation

Abstract

All Science Journal Classification (ASJC) codes

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