Abstract
Natural products are the basis of time-honored folk medicines and many of our most successful pJiarmaceuticals, and liave stimulated profound advances in organic chemistry. Hie breath-taking multiformity of natural products fuels the drug discovery process and provides abundant opportunities for creative research in organic synthesis. Today, the cliallenge and necessity of defining concise pathways for the chemical synthesis of natural products and related structures possessing useful biological properties compels research in organic synthesis. This revieiv addresses selected, recent achievements in this field.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 606-630 |
| Number of pages | 25 |
| Journal | Current Opinion in Drug Discovery and Development |
| Volume | 2 |
| Issue number | 6 |
| State | Published - 1999 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Pharmacology
Keywords
- Diversity
- Natural products
- Total synthesis