Selected, recent developments in the chemical synthesis of biologicallyactive natural products

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Abstract

Natural products are the basis of time-honored folk medicines and many of our most successful pJiarmaceuticals, and liave stimulated profound advances in organic chemistry. Hie breath-taking multiformity of natural products fuels the drug discovery process and provides abundant opportunities for creative research in organic synthesis. Today, the cliallenge and necessity of defining concise pathways for the chemical synthesis of natural products and related structures possessing useful biological properties compels research in organic synthesis. This revieiv addresses selected, recent achievements in this field.

Original languageEnglish (US)
Pages (from-to)606-630
Number of pages25
JournalCurrent Opinion in Drug Discovery and Development
Volume2
Issue number6
StatePublished - Dec 1 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Pharmacology
  • Drug Discovery

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