Role Reversal: A Pro-metastatic Function of E-Cadherin

Minhong Shen, Yibin Kang

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations


Carcinoma cells often acquire mobility and invasiveness by undergoing epithelial-to-mesenchymal transition, and yet most metastatic lesions remain epithelial in nature. Recently, in Nature, Padmanaban et al. (2019) demonstrated that the quintessential epithelial marker E-cadherin promotes metastasis of invasive ductal breast carcinoma by enhancing the survival of tumor cells.

Original languageEnglish (US)
Pages (from-to)417-419
Number of pages3
JournalDevelopmental cell
Issue number4
StatePublished - Nov 18 2019

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology
  • Molecular Biology
  • Cell Biology
  • Developmental Biology


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