Rhodium-catalyzed oxidative cycloaddition of benzamides and alkynes via C-H/N-H activation

Keyphrases

• Alkynes 100%
• Benzamide 100%
• N-H Activation 100%
• Diels-Alder Cycloaddition 100%
• Rhodium-catalyzed 100%
• Amides 66%
• Heteroaryl 33%
• Arenes 33%
• C-H Activation 33%
• Metalation 33%
• Ortho 33%
• Rh(III) Catalyst 33%
• Rhodacycle 33%
• Halides 33%
• Regioselectivity 33%
• Cu(II) 33%
• Aldehydes 33%
• Medicinal Chemistry 33%
• Alkyne Insertion 33%
• Competition Experiments 33%
• Isoquinolones 33%
• Carboxamide 33%
• Unsymmetrical Alkynes 33%
• Good Yields 33%
• Silyl Ether 33%

Chemistry

• Rhodium 100%
• Benzamide 100%
• Oxidative Cycloaddition 100%
• Alkyne 100%
• Carboxamide 60%
• Halide 20%
• Chemistry 20%
• Metalation 20%
• Regioselectivity 20%
• Silyl Ether 20%
• Aldehyde 20%
• Catalyst 20%