Rhodium-catalyzed oxidative carbonylation of benzamides with CO under mild conditions

Ya Du, Todd K. Hyster, Tomislav Rovis

Research output: Contribution to journalConference article

Abstract

An efficient strategy for the oxidative carbonylation of benzamides via C-H/N-H activation to form phthalimides has been developed. The reaction utilizes Rh(III) catalyst in the presence of Ag(I) oxidant, and is proposed to proceed by N-H metalation of the amide followed by ortho C-H activation. The resultant rhodacycle undergoes CO insertion to form phthalimides in good to excellent yields.

Original languageEnglish (US)
JournalACS National Meeting Book of Abstracts
StatePublished - Dec 1 2011
Externally publishedYes
Event242nd ACS National Meeting and Exposition - Denver, CO, United States
Duration: Aug 28 2011Sep 1 2011

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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