Rhodium-catalyzed oxidative carbonylation of benzamides with CO under mild conditions

Ya Du; Todd K. Hyster; Tomislav Rovis

Rhodium-catalyzed oxidative carbonylation of benzamides with CO under mild conditions

Ya Du, Todd K. Hyster, Tomislav Rovis

Research output: Contribution to journal › Conference article › peer-review

Abstract

An efficient strategy for the oxidative carbonylation of benzamides via C-H/N-H activation to form phthalimides has been developed. The reaction utilizes Rh(III) catalyst in the presence of Ag(I) oxidant, and is proposed to proceed by N-H metalation of the amide followed by ortho C-H activation. The resultant rhodacycle undergoes CO insertion to form phthalimides in good to excellent yields.

Original language	English (US)
Journal	ACS National Meeting Book of Abstracts
State	Published - Dec 1 2011
Externally published	Yes
Event	242nd ACS National Meeting and Exposition - Denver, CO, United States Duration: Aug 28 2011 → Sep 1 2011

All Science Journal Classification (ASJC) codes

Chemistry(all)
Chemical Engineering(all)

Cite this

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title = "Rhodium-catalyzed oxidative carbonylation of benzamides with CO under mild conditions",

abstract = "An efficient strategy for the oxidative carbonylation of benzamides via C-H/N-H activation to form phthalimides has been developed. The reaction utilizes Rh(III) catalyst in the presence of Ag(I) oxidant, and is proposed to proceed by N-H metalation of the amide followed by ortho C-H activation. The resultant rhodacycle undergoes CO insertion to form phthalimides in good to excellent yields.",

author = "Ya Du and Hyster, {Todd K.} and Tomislav Rovis",

year = "2011",

month = dec,

day = "1",

language = "English (US)",

journal = "ACS National Meeting Book of Abstracts",

issn = "0065-7727",

publisher = "American Chemical Society",

note = "242nd ACS National Meeting and Exposition ; Conference date: 28-08-2011 Through 01-09-2011",

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T1 - Rhodium-catalyzed oxidative carbonylation of benzamides with CO under mild conditions

AU - Du, Ya

AU - Hyster, Todd K.

AU - Rovis, Tomislav

PY - 2011/12/1

Y1 - 2011/12/1

N2 - An efficient strategy for the oxidative carbonylation of benzamides via C-H/N-H activation to form phthalimides has been developed. The reaction utilizes Rh(III) catalyst in the presence of Ag(I) oxidant, and is proposed to proceed by N-H metalation of the amide followed by ortho C-H activation. The resultant rhodacycle undergoes CO insertion to form phthalimides in good to excellent yields.

AB - An efficient strategy for the oxidative carbonylation of benzamides via C-H/N-H activation to form phthalimides has been developed. The reaction utilizes Rh(III) catalyst in the presence of Ag(I) oxidant, and is proposed to proceed by N-H metalation of the amide followed by ortho C-H activation. The resultant rhodacycle undergoes CO insertion to form phthalimides in good to excellent yields.

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M3 - Conference article

AN - SCOPUS:84861071958

SN - 0065-7727

JO - ACS National Meeting Book of Abstracts

JF - ACS National Meeting Book of Abstracts

T2 - 242nd ACS National Meeting and Exposition

Y2 - 28 August 2011 through 1 September 2011

ER -

Rhodium-catalyzed oxidative carbonylation of benzamides with CO under mild conditions

Abstract

All Science Journal Classification (ASJC) codes

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