Response of dopaminergic neurons in cat to auditory stimuli presented across the sleep-waking cycle

George F. Steinfels, James Heym, Robert E. Strecker, Barry L. Jacobs

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

The response of dopaminergic neurons of the substantia nigra pars compacta to auditory clicks continuously presented across the sleep-wake cycle was studied in cats. The initial excitatory followed by inhibitory response to the click which occurred during quiet waking diminished as the cat progressed into slow-wave sleep and was absent during REM sleep. Upon awakening from REM sleep, dopamine neurons once again displayed an excitatory/inhibitory response to the clicks, implying that the decrease across the sleep-wake cycle was not attributable to long-term habituation.

Original languageEnglish (US)
Pages (from-to)150-154
Number of pages5
JournalBrain Research
Volume277
Issue number1
DOIs
StatePublished - Oct 24 1983

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Keywords

  • REM sleep
  • auditory stimulation
  • dopamine
  • dopaminergic unit activity
  • sleep-waking
  • substantia nigra

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