Rescuing US biomedical research from its systemic flaws

Bruce Alberts; Marc W. Kirschner; Shirley Tilghman; Harold Varmus

doi:10.1073/pnas.1404402111

Rescuing US biomedical research from its systemic flaws

Bruce Alberts, Marc W. Kirschner, Shirley Tilghman, Harold Varmus

Research output: Contribution to journal › Review article › peer-review

553 Scopus citations

Abstract

The long-held but erroneous assumption of never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession - and making it difficult for seasoned investigators to produce their best work. This is a recipe for long-term decline, and the problems cannot be solved with simplistic approaches. Instead, it is time to confront the dangers at hand and rethink some fundamental features of the US biomedical research ecosystem.

Original language	English (US)
Pages (from-to)	5773-5777
Number of pages	5
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	111
Issue number	16
DOIs	https://doi.org/10.1073/pnas.1404402111
State	Published - Apr 22 2014

All Science Journal Classification (ASJC) codes

General

Keywords

Federal funding
Graduate education
Peer review
Postdoctoral education

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10.1073/pnas.1404402111

Cite this

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AU - Tilghman, Shirley

AU - Varmus, Harold

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Y1 - 2014/4/22

N2 - The long-held but erroneous assumption of never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession - and making it difficult for seasoned investigators to produce their best work. This is a recipe for long-term decline, and the problems cannot be solved with simplistic approaches. Instead, it is time to confront the dangers at hand and rethink some fundamental features of the US biomedical research ecosystem.

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KW - Federal funding

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KW - Peer review

KW - Postdoctoral education

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Rescuing US biomedical research from its systemic flaws

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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