TY - JOUR
T1 - Regulation of tissue morphodynamics
T2 - An important role for actomyosin contractility
AU - Siedlik, Michael J.
AU - Nelson, Celeste M.
N1 - Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Forces arising from contractile actomyosin filaments help shape tissue form during morphogenesis. Developmental events that result from actomyosin contractility include tissue elongation, bending, budding, and collective migration. Here, we highlight recent insights into these morphogenetic processes from the perspective of actomyosin contractility as a key regulator. Emphasis is placed on a range of results obtained through live imaging, culture, and computational methods. Combining these approaches in the future has the potential to generate a robust, quantitative understanding of tissue morphodynamics.
AB - Forces arising from contractile actomyosin filaments help shape tissue form during morphogenesis. Developmental events that result from actomyosin contractility include tissue elongation, bending, budding, and collective migration. Here, we highlight recent insights into these morphogenetic processes from the perspective of actomyosin contractility as a key regulator. Emphasis is placed on a range of results obtained through live imaging, culture, and computational methods. Combining these approaches in the future has the potential to generate a robust, quantitative understanding of tissue morphodynamics.
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U2 - 10.1016/j.gde.2015.01.002
DO - 10.1016/j.gde.2015.01.002
M3 - Review article
C2 - 25748251
AN - SCOPUS:84924083377
SN - 0959-437X
VL - 32
SP - 80
EP - 85
JO - Current Opinion in Genetics and Development
JF - Current Opinion in Genetics and Development
ER -