Regioselective nucleophilic substitutions of fluorobenzene derivatives

Kenneth M. Wells, Yao Jun Shi, Joseph E. Lynch, Guy R. Humphrey, R. P. Volante, Paul J. Reider

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Regioselective nucleophilic substitutions of tri- and di-substituted fluorobenzoates, fluorobenzonitriles, and fluoronitrobenzenes were accomplished by sequential addition of various nucleophiles, such as, potassium N-Boc-4-piperidinyl oxide, potassium methoxide, and piperidine.

Original languageEnglish (US)
Pages (from-to)6439-6442
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number36
DOIs
StatePublished - Sep 2 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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