Regio- and stereocontrolled syntheses of cyclic chiral cis-amino alcohols from 1,2-diols or epoxides

Chris H. Senanayake, Lisa M. DiMichele, Ji Liu, Laura E. Fredenburgh, Kenneth M. Ryan, F. Edward Roberts, Robert D. Larsen, Thomas R. Verhoeven, Paul J. Reider

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Abstract

The behavior of 1,2-dioxygen derivatives of indane, tetralin, and benzosuberane in acetonitrile-strong acid media is exploited in the regio- and stereocontrolled syntheses of chiral cis-amino alcohols.

Original languageEnglish (US)
Pages (from-to)7615-7618
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number42
DOIs
StatePublished - Oct 16 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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    Senanayake, C. H., DiMichele, L. M., Liu, J., Fredenburgh, L. E., Ryan, K. M., Edward Roberts, F., Larsen, R. D., Verhoeven, T. R., & Reider, P. J. (1995). Regio- and stereocontrolled syntheses of cyclic chiral cis-amino alcohols from 1,2-diols or epoxides. Tetrahedron Letters, 36(42), 7615-7618. https://doi.org/10.1016/0040-4039(95)01583-4