Regio- and stereocontrolled syntheses of cyclic chiral cis-amino alcohols from 1,2-diols or epoxides

Chris H. Senanayake, Lisa M. DiMichele, Ji Liu, Laura E. Fredenburgh, Kenneth M. Ryan, F. Edward Roberts, Robert D. Larsen, Thomas R. Verhoeven, Paul J. Reider

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

The behavior of 1,2-dioxygen derivatives of indane, tetralin, and benzosuberane in acetonitrile-strong acid media is exploited in the regio- and stereocontrolled syntheses of chiral cis-amino alcohols.

Original languageEnglish (US)
Pages (from-to)7615-7618
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number42
DOIs
StatePublished - Oct 16 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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