Red-emitting, EtTP-5-based organic nanoprobes for two-photon imaging in 3D multicellular biological models

Nathalie M. Pinkerton; Céline Frongia; Valérie Lobjois; Brian K. Wilson; Matthew J. Bruzek; Robert K. Prud'Homme; John Anthony; Frédéric Bolze; Stefan Chassaing

doi:10.1039/c6ra09954h

Red-emitting, EtTP-5-based organic nanoprobes for two-photon imaging in 3D multicellular biological models

Nathalie M. Pinkerton
, Céline Frongia
, Valérie Lobjois
, Brian K. Wilson
, Matthew J. Bruzek
, Robert K. Prud'Homme
, John Anthony
, Frédéric Bolze
, Stefan Chassaing

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Biocompatible and biostable EtTP-5-loaded organic core-shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging. Readily formed by Flash NanoPrecipitation, EtTP-5-based nanoprobes proved to penetrate well into multicellular spheroids and were easily imaged through several cell layers within these complex, 3D tissue models.

Original language	English (US)
Pages (from-to)	65770-65774
Number of pages	5
Journal	RSC Advances
Volume	6
Issue number	70
DOIs	https://doi.org/10.1039/c6ra09954h
State	Published - 2016

All Science Journal Classification (ASJC) codes

General Chemistry
General Chemical Engineering

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10.1039/c6ra09954h

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title = "Red-emitting, EtTP-5-based organic nanoprobes for two-photon imaging in 3D multicellular biological models",

abstract = "Biocompatible and biostable EtTP-5-loaded organic core-shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging. Readily formed by Flash NanoPrecipitation, EtTP-5-based nanoprobes proved to penetrate well into multicellular spheroids and were easily imaged through several cell layers within these complex, 3D tissue models.",

author = "Pinkerton, \{Nathalie M.\} and C{\'e}line Frongia and Val{\'e}rie Lobjois and Wilson, \{Brian K.\} and Bruzek, \{Matthew J.\} and Prud'Homme, \{Robert K.\} and John Anthony and Fr{\'e}d{\'e}ric Bolze and Stefan Chassaing",

note = "Publisher Copyright: This journal is {\textcopyright} The Royal Society of Chemistry 2016.",

year = "2016",

doi = "10.1039/c6ra09954h",

language = "English (US)",

volume = "6",

pages = "65770--65774",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

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}

TY - JOUR

T1 - Red-emitting, EtTP-5-based organic nanoprobes for two-photon imaging in 3D multicellular biological models

AU - Pinkerton, Nathalie M.

AU - Frongia, Céline

AU - Lobjois, Valérie

AU - Wilson, Brian K.

AU - Bruzek, Matthew J.

AU - Prud'Homme, Robert K.

AU - Anthony, John

AU - Bolze, Frédéric

AU - Chassaing, Stefan

PY - 2016

Y1 - 2016

N2 - Biocompatible and biostable EtTP-5-loaded organic core-shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging. Readily formed by Flash NanoPrecipitation, EtTP-5-based nanoprobes proved to penetrate well into multicellular spheroids and were easily imaged through several cell layers within these complex, 3D tissue models.

AB - Biocompatible and biostable EtTP-5-loaded organic core-shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging. Readily formed by Flash NanoPrecipitation, EtTP-5-based nanoprobes proved to penetrate well into multicellular spheroids and were easily imaged through several cell layers within these complex, 3D tissue models.

UR - https://www.scopus.com/pages/publications/84978483981

UR - https://www.scopus.com/pages/publications/84978483981#tab=citedBy

U2 - 10.1039/c6ra09954h

DO - 10.1039/c6ra09954h

M3 - Article

AN - SCOPUS:84978483981

SN - 2046-2069

VL - 6

SP - 65770

EP - 65774

JO - RSC Advances

JF - RSC Advances

IS - 70

ER -

Red-emitting, EtTP-5-based organic nanoprobes for two-photon imaging in 3D multicellular biological models

Abstract

All Science Journal Classification (ASJC) codes

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