Recording of dorsal raphe unit activity in vitro

Sarah S. Mosko; Barry L. Jacobs

doi:10.1016/0304-3940(76)90014-8

Recording of dorsal raphe unit activity in vitro

Sarah S. Mosko, Barry L. Jacobs

Psychology

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

The spontaneous electrical activity of single neurons of the midbrain dorsal raphe nucleus in the rat was recorded in vitro in 400 μm thick slices. The majority of raphe neurons exhibited the slow and regular discharge pattern that characterizes the activity of raphe neurons when recorded in vivo. The viability of these neurons in vitro thus provides a preparation for analyzing endogenous and exogenous factors that regulate the activity of these serotonin-containing neurons.

Original language	English (US)
Pages (from-to)	195-200
Number of pages	6
Journal	Neuroscience Letters
Volume	2
Issue number	4
DOIs	https://doi.org/10.1016/0304-3940(76)90014-8
State	Published - Jun 1976

All Science Journal Classification (ASJC) codes

General Neuroscience

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10.1016/0304-3940(76)90014-8

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title = "Recording of dorsal raphe unit activity in vitro",

abstract = "The spontaneous electrical activity of single neurons of the midbrain dorsal raphe nucleus in the rat was recorded in vitro in 400 μm thick slices. The majority of raphe neurons exhibited the slow and regular discharge pattern that characterizes the activity of raphe neurons when recorded in vivo. The viability of these neurons in vitro thus provides a preparation for analyzing endogenous and exogenous factors that regulate the activity of these serotonin-containing neurons.",

author = "Mosko, {Sarah S.} and Jacobs, {Barry L.}",

note = "Funding Information: We wish to thank Gary S. Lynch for his generosity and assistance. This research was supported by NIMH Grant MH 23433 and the Spencer Foundation.",

year = "1976",

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T1 - Recording of dorsal raphe unit activity in vitro

AU - Mosko, Sarah S.

AU - Jacobs, Barry L.

N1 - Funding Information: We wish to thank Gary S. Lynch for his generosity and assistance. This research was supported by NIMH Grant MH 23433 and the Spencer Foundation.

PY - 1976/6

Y1 - 1976/6

N2 - The spontaneous electrical activity of single neurons of the midbrain dorsal raphe nucleus in the rat was recorded in vitro in 400 μm thick slices. The majority of raphe neurons exhibited the slow and regular discharge pattern that characterizes the activity of raphe neurons when recorded in vivo. The viability of these neurons in vitro thus provides a preparation for analyzing endogenous and exogenous factors that regulate the activity of these serotonin-containing neurons.

AB - The spontaneous electrical activity of single neurons of the midbrain dorsal raphe nucleus in the rat was recorded in vitro in 400 μm thick slices. The majority of raphe neurons exhibited the slow and regular discharge pattern that characterizes the activity of raphe neurons when recorded in vivo. The viability of these neurons in vitro thus provides a preparation for analyzing endogenous and exogenous factors that regulate the activity of these serotonin-containing neurons.

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JO - Neuroscience Letters

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IS - 4

ER -

Recording of dorsal raphe unit activity in vitro

Abstract

All Science Journal Classification (ASJC) codes

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