Recent advances of laser-spectroscopybased techniques for applications in breath analysis

Matthew R. McCurdy, Yury Bakhirkin, Gerard Wysocki, Rafal Lewicki, Frank K. Tittel

Research output: Contribution to journalReview article

161 Scopus citations

Abstract

Laser absorption spectroscopy (LAS) in the mid-infrared region offers a promising new effective technique for the quantitative analysis of trace gases in human breath. LAS enables sensitive, selective detection, quantification and monitoring in real time, of gases present in breath. This review summarizes some of the recent advances in LAS based on semiconductor lasers and optical detection techniques for clinically relevant exhaled gas analysis in breath, specifically such molecular biomarkers as nitric oxide, ammonia, carbon monoxide, ethane, carbonyl sulfide, formaldehyde and acetone.

Original languageEnglish (US)
JournalJournal of Breath Research
Volume1
Issue number1
DOIs
StatePublished - Jul 11 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

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