Recent advances in the application of expressed protein ligation to protein engineering

Roseanne M. Hofmann, Tom W. Muir

Research output: Contribution to journalReview articlepeer-review

74 Scopus citations

Abstract

Expressed protein ligation is a technique for joining recombinantly expressed proteins to polypeptides containing biophysical probes, post-translational modifications or unnatural amino acids. Recent advances have expanded the scope of expressed protein ligation and have allowed the approach to be applied to the study of basic biological questions.

Original languageEnglish (US)
Pages (from-to)297-303
Number of pages7
JournalCurrent Opinion in Biotechnology
Volume13
Issue number4
DOIs
StatePublished - Aug 1 2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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