Rapid and quantitative sizing of nanoparticles using three-dimensional single-particle tracking

C. Shan Xu; Hu Cang; Daniel Montiel; Haw Yang

doi:10.1021/jp0671796

Rapid and quantitative sizing of nanoparticles using three-dimensional single-particle tracking

C. Shan Xu, Hu Cang, Daniel Montiel, Haw Yang

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

We report the first application of three-dimensional (3D) single-particle tracking (SPT) to hydrodynamic size characterization of gold nanoparticles in water. Nanoparticles undergoing Brownian motion were dynamically locked at the focal point of a microscope objective, one at a time, by rapid counteractive movements of the sample container. The hydrodynamic radius was derived from the recorded trajectory of each individual nanoparticle. The directly measured size and size distribution using 3D-SPT were in agreement with those obtained using the conventional dynamic light scattering (DLS) and using transmission electron microscopy (TEM), respectively.

Original language	English (US)
Pages (from-to)	32-35
Number of pages	4
Journal	Journal of Physical Chemistry C
Volume	111
Issue number	1
DOIs	https://doi.org/10.1021/jp0671796
State	Published - Jan 11 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
General Energy
Physical and Theoretical Chemistry
Surfaces, Coatings and Films

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10.1021/jp0671796

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AB - We report the first application of three-dimensional (3D) single-particle tracking (SPT) to hydrodynamic size characterization of gold nanoparticles in water. Nanoparticles undergoing Brownian motion were dynamically locked at the focal point of a microscope objective, one at a time, by rapid counteractive movements of the sample container. The hydrodynamic radius was derived from the recorded trajectory of each individual nanoparticle. The directly measured size and size distribution using 3D-SPT were in agreement with those obtained using the conventional dynamic light scattering (DLS) and using transmission electron microscopy (TEM), respectively.

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Rapid and quantitative sizing of nanoparticles using three-dimensional single-particle tracking

Abstract

All Science Journal Classification (ASJC) codes

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