RAI2: Linking retinoic acid signaling with metastasis suppression

Mark Esposito; Yibin Kang

doi:10.1158/2159-8290.CD-15-0352

RAI2: Linking retinoic acid signaling with metastasis suppression

Mark Esposito, Yibin Kang

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Considerable evidence points to the importance of disseminated tumor cells, which are commonly detected in the bone marrow and display features of cellular plasticity, in predicting the clinical outcome of breast cancer. In this issue of Cancer Discovery, Werner and colleagues report on the discovery of retinoic acid–induced 2 (RAI2) as a differentiation factor that suppresses early metastatic spread of estrogen receptor–positive breast cancer.

Original language	English (US)
Pages (from-to)	466-468
Number of pages	3
Journal	Cancer Discovery
Volume	5
Issue number	5
DOIs	https://doi.org/10.1158/2159-8290.CD-15-0352
State	Published - May 2015

All Science Journal Classification (ASJC) codes

Oncology

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10.1158/2159-8290.CD-15-0352

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title = "RAI2: Linking retinoic acid signaling with metastasis suppression",

abstract = "Considerable evidence points to the importance of disseminated tumor cells, which are commonly detected in the bone marrow and display features of cellular plasticity, in predicting the clinical outcome of breast cancer. In this issue of Cancer Discovery, Werner and colleagues report on the discovery of retinoic acid–induced 2 (RAI2) as a differentiation factor that suppresses early metastatic spread of estrogen receptor–positive breast cancer.",

author = "Mark Esposito and Yibin Kang",

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AB - Considerable evidence points to the importance of disseminated tumor cells, which are commonly detected in the bone marrow and display features of cellular plasticity, in predicting the clinical outcome of breast cancer. In this issue of Cancer Discovery, Werner and colleagues report on the discovery of retinoic acid–induced 2 (RAI2) as a differentiation factor that suppresses early metastatic spread of estrogen receptor–positive breast cancer.

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RAI2: Linking retinoic acid signaling with metastasis suppression

Abstract

All Science Journal Classification (ASJC) codes

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