Quantitative evaluation of cross correlation between two finite-length time series with applications to single-molecule FRET

Jeffery A. Hanson, Haw Yang

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

The statistical properties of the cross correlation between two time series has been studied. An analytical expression for the cross correlation function's variance has been derived. On the basis of these results, a statistically robust method has been proposed to detect the existence and determine the direction of cross correlation between two time series. The proposed method has been characterized by computer simulations. Applications to single-molecule fluorescence spectroscopy are discussed. The results may also find immediate applications in fluorescence correlation spectroscopy (FCS) and its variants.

Original languageEnglish (US)
Pages (from-to)13962-13970
Number of pages9
JournalJournal of Physical Chemistry B
Volume112
Issue number44
DOIs
StatePublished - Nov 6 2008

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films
  • Materials Chemistry

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