Quantifying Current Events Identifies a Novel Endurance Regulator

Theresa C. Henry, Mark P. Brynildsen

Research output: Contribution to journalShort surveypeer-review

Abstract

In nongrowing microbes, proteome turnover is reduced and identification of newly synthesized, low-abundance proteins is challenging. Babin and colleagues recently utilized bio-orthogonal noncanonical amino acid tagging (BONCAT) to identify actively synthesized proteins in nongrowing Pseudomonas aeruginosa, discovering a regulator whose influences range from biofilm formation to secondary metabolism.

Original languageEnglish (US)
Pages (from-to)324-326
Number of pages3
JournalTrends in Microbiology
Volume24
Issue number5
DOIs
StatePublished - May 1 2016

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

Keywords

  • BONCAT
  • Nongrowing cells
  • Pseudomonas aeruginosa
  • SutA
  • Transcription

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