Pseudorabies virus glycoprotein gIII is required for efficient virus growth in tissue culture.

M. E. Whealy, A. K. Robbins, L. W. Enquist

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Glycoprotein gIII of pseudorabies virus is a major antigen found in the envelopes of virus particles as well as in and on the surfaces of infected cells. It is not an essential gene product for virus growth in tissue culture. In this report, we provide evidence that, although it is not essential, the gIII protein is required for efficient virus growth and that gIII mutants are quickly outgrown by wild-type virus in mixed infections.

Original languageEnglish (US)
Pages (from-to)2512-2515
Number of pages4
JournalJournal of virology
Volume62
Issue number7
DOIs
StatePublished - Jul 1988
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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