Progress in single-molecule spectroscopy in cells

Haw Yang

doi:10.1016/j.cbpa.2009.10.015

Progress in single-molecule spectroscopy in cells

Haw Yang

Chemistry

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Time-dependent single-molecule spectroscopy allows the direct observation of molecular processes in real time, capturing transient and stochastic events that cannot be detected using conventional ensemble-averaged methods. It offers a promising approach to uncovering the physical and chemical transformations underlying cellular responses. Recent advances in the probe development, specific labeling strategies, and spectroscopy instrumentation suggest the feasibility of monitoring a single molecular machine's actions inside a living cell.

Original language	English (US)
Pages (from-to)	3-9
Number of pages	7
Journal	Current Opinion in Chemical Biology
Volume	14
Issue number	1
DOIs	https://doi.org/10.1016/j.cbpa.2009.10.015
State	Published - Feb 2010

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry

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10.1016/j.cbpa.2009.10.015

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abstract = "Time-dependent single-molecule spectroscopy allows the direct observation of molecular processes in real time, capturing transient and stochastic events that cannot be detected using conventional ensemble-averaged methods. It offers a promising approach to uncovering the physical and chemical transformations underlying cellular responses. Recent advances in the probe development, specific labeling strategies, and spectroscopy instrumentation suggest the feasibility of monitoring a single molecular machine's actions inside a living cell.",

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Progress in single-molecule spectroscopy in cells

Abstract

All Science Journal Classification (ASJC) codes

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