TY - JOUR
T1 - Primate-to-human retroviral transmission in Asia
AU - Jones-Engel, Lisa
AU - Engel, Gregory A.
AU - Schillaci, Michael A.
AU - Rompis, Aida
AU - Putra, Artha
AU - Suaryana, Komang Gde
AU - Fuentes, Agustin
AU - Beer, Brigitte
AU - Hicks, Sarah
AU - White, Robert
AU - Wilson, Brenda
AU - Allan, Jonathan S.
PY - 2005/7
Y1 - 2005/7
N2 - We describe the first reported transmission to a human of simian foamy virus (SFV) from a free-ranging population of nonhuman primates in Asia. The transmission of an exogenous retrovirus, SFV, from macaques (Macaca fascicularis) to a human at a monkey temple in Bali, Indonesia, was investigated with molecular and serologic techniques. Antibodies to SFV were detected by Western blotting of serum from 1 of 82 humans tested. SFV DNA was detected by nested polymerase chain reaction (PCR) from the blood of the same person. Cloning and sequencing of PCR products confirmed the virus's close phylogenetic relationship to SFV isolated from macaques at the same temple. This study raises concerns that persons who work at or live around monkey temples are at risk for infection with SFV.
AB - We describe the first reported transmission to a human of simian foamy virus (SFV) from a free-ranging population of nonhuman primates in Asia. The transmission of an exogenous retrovirus, SFV, from macaques (Macaca fascicularis) to a human at a monkey temple in Bali, Indonesia, was investigated with molecular and serologic techniques. Antibodies to SFV were detected by Western blotting of serum from 1 of 82 humans tested. SFV DNA was detected by nested polymerase chain reaction (PCR) from the blood of the same person. Cloning and sequencing of PCR products confirmed the virus's close phylogenetic relationship to SFV isolated from macaques at the same temple. This study raises concerns that persons who work at or live around monkey temples are at risk for infection with SFV.
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U2 - 10.3201/eid1107.040957
DO - 10.3201/eid1107.040957
M3 - Article
C2 - 16022776
AN - SCOPUS:21144453476
SN - 1080-6040
VL - 11
SP - 1028
EP - 1035
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 7
ER -