Preparation of aggregation stable block copolymer nanoparticles for simultaneous drug delivery and imaging

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a novel process for the simultaneous encapsulation of active pharmaceutical compounds (βcarotene, α-tocopherol succinate) and imaging agents (dodecanethiol gold nanoparticles and 7-amino-4-methyl coumarin) based on diblock copolymer self assembly in the diffusion limited regime. Uniform particles with tunable sizes from 50-300 nm and long term stability are prepared at high concentrations of incorporated compound. The degree of agent loading is varied independently of particle size, allowing for precise control of system parameters.

Original languageEnglish (US)
Title of host publication2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
Pages448-450
Number of pages3
Volume2
StatePublished - Dec 8 2006
Event2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings - Boston, MA, United States
Duration: May 7 2006May 11 2006

Other

Other2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
CountryUnited States
CityBoston, MA
Period5/7/065/11/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Fingerprint Dive into the research topics of 'Preparation of aggregation stable block copolymer nanoparticles for simultaneous drug delivery and imaging'. Together they form a unique fingerprint.

  • Cite this

    Gindy, M., & Prud'homme, R. K. (2006). Preparation of aggregation stable block copolymer nanoparticles for simultaneous drug delivery and imaging. In 2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings (Vol. 2, pp. 448-450)