Practical asymmetric synthesis of aprepitant, a potent human NK-1 receptor antagonist, via a stereoselective Lewis acid-catalyzed trans acetalization reaction

Matthew M. Zhao, James M. McNamara, Guo Jie Ho, Khateeta M. Emerson, Zhiguo J. Song, David M. Tschaen, Karel M.J. Brands, Ulf H. Dolling, Edward J.J. Grabowski, Paul J. Reider, Ian F. Cottrell, Michael S. Ashwood, Brian C. Bishop

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Fingerprint

Dive into the research topics of 'Practical asymmetric synthesis of aprepitant, a potent human NK-1 receptor antagonist, via a stereoselective Lewis acid-catalyzed trans acetalization reaction'. Together they form a unique fingerprint.

Keyphrases

Chemistry