Positional Information and Cell Fate Determination in the Early Drosophila Embryo

Eric Wieschaus

Research output: Chapter in Book/Report/Conference proceedingChapter

22 Scopus citations


During early development in Drosophila, the spatial information of maternal gradients is translated into discrete transcriptional states determining cell fate. Information transfer depends on reproducibility of the gradients themselves, as well as the ability of cells to accurately measure and utilize morphogen concentrations in biologically meaning ways. In the following essay, these issues are discussed in context of the Bicoid gradient.

Original languageEnglish (US)
Title of host publicationCurrent Topics in Developmental Biology
PublisherAcademic Press Inc.
Number of pages13
StatePublished - Dec 1 2016

Publication series

NameCurrent Topics in Developmental Biology
ISSN (Print)0070-2153

All Science Journal Classification (ASJC) codes

  • Cell Biology
  • Developmental Biology


  • Bicoid
  • Blastoderm
  • Compartments
  • Drosophila embryo
  • Maternal gradients
  • Midblastula transition
  • Pattern formation
  • Positional information


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