Polydopamine-based nanoreactors: Synthesis and applications in bioscience and energy materials

Shilin Mei, Xiaohui Xu, Rodney D. Priestley, Yan Lu

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations


Polydopamine (PDA)-based nanoreactors have shown exceptional promise as multifunctional materials due to their nanoscale dimensions and sub-microliter volumes for reactions of different systems. Biocompatibility, abundance of active sites, and excellent photothermal conversion have facilitated their extensive use in bioscience and energy storage/conversion. This minireview summarizes recent advances in PDA-based nanoreactors, as applied to the abovementioned fields. We first highlight the design and synthesis of functional PDA-based nanoreactors with structural and compositional diversity. Special emphasis in bioscience has been given to drug/protein delivery, photothermal therapy, and antibacterial properties, while for energy-related applications, the focus is on electrochemical energy storage, catalysis, and solar energy harvesting. In addition, perspectives on pressing challenges and future research opportunities regarding PDA-based nanoreactors are discussed.

Original languageEnglish (US)
Pages (from-to)12269-12281
Number of pages13
JournalChemical Science
Issue number45
StatePublished - Dec 7 2020

All Science Journal Classification (ASJC) codes

  • General Chemistry


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