Picosecond IR dynamics: Lessons learned

Robert Austin; Aihua Xie

doi:10.1016/S0168-9002(98)00077-1

Picosecond IR dynamics: Lessons learned

Robert Austin
, Aihua Xie

Research output: Contribution to journal › Conference article › peer-review

5 Scopus citations

Abstract

Time-resolved infrared (IR) pump-probe experiments were conducted at FELIX, the free electron laser (FEL) at Nieuwegein, The Netherlands. The study aims to measure the relaxation time, both longitudinal and transverse, of protein molecules at the amide I band and in the far-IR band. To address the problem of high differential sensitivity, the dual element detector approach and the single element approach were applied.

Original language	English (US)
Pages (from-to)	504-508
Number of pages	5
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	407
Issue number	1-3
DOIs	https://doi.org/10.1016/S0168-9002(98)00077-1
State	Published - 1998
Event	Proceedings of the 1997 19th International Free Electron Laser Conference and 4th FEL Users' Workshop - Beijing, China Duration: Aug 18 1997 → Aug 22 1997

All Science Journal Classification (ASJC) codes

Nuclear and High Energy Physics
Instrumentation

Access to Document

10.1016/S0168-9002(98)00077-1

Cite this

@article{d50959d251a64b399497f767bbbc7b22,

title = "Picosecond IR dynamics: Lessons learned",

abstract = "Time-resolved infrared (IR) pump-probe experiments were conducted at FELIX, the free electron laser (FEL) at Nieuwegein, The Netherlands. The study aims to measure the relaxation time, both longitudinal and transverse, of protein molecules at the amide I band and in the far-IR band. To address the problem of high differential sensitivity, the dual element detector approach and the single element approach were applied.",

author = "Robert Austin and Aihua Xie",

note = "Funding Information: We sincerely hope that at this point we have made all the possible mistakes that you can make in picosecond IR pump-probe experiments on hydrated protein samples. The last run using a liquid amino acid analog sample (asparagine) indicated that pump-probe signals showing saturation recovery of the amide I band were at the 1\% level with 1 μJ micropulse energies. We hope that at FELIX a deep understanding of energy flow and transfer in biomolecules will develop. We are grateful to the patience shown by the FELIX staff, and generous support by the Office of Naval Research Medical Free Electron Laser Program.; Proceedings of the 1997 19th International Free Electron Laser Conference and 4th FEL Users' Workshop ; Conference date: 18-08-1997 Through 22-08-1997",

year = "1998",

doi = "10.1016/S0168-9002(98)00077-1",

language = "English (US)",

volume = "407",

pages = "504--508",

journal = "Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment",

issn = "0168-9002",

publisher = "Elsevier B.V.",

number = "1-3",

}

TY - JOUR

T1 - Picosecond IR dynamics

T2 - Proceedings of the 1997 19th International Free Electron Laser Conference and 4th FEL Users' Workshop

AU - Austin, Robert

AU - Xie, Aihua

N1 - Funding Information: We sincerely hope that at this point we have made all the possible mistakes that you can make in picosecond IR pump-probe experiments on hydrated protein samples. The last run using a liquid amino acid analog sample (asparagine) indicated that pump-probe signals showing saturation recovery of the amide I band were at the 1% level with 1 μJ micropulse energies. We hope that at FELIX a deep understanding of energy flow and transfer in biomolecules will develop. We are grateful to the patience shown by the FELIX staff, and generous support by the Office of Naval Research Medical Free Electron Laser Program.

PY - 1998

Y1 - 1998

N2 - Time-resolved infrared (IR) pump-probe experiments were conducted at FELIX, the free electron laser (FEL) at Nieuwegein, The Netherlands. The study aims to measure the relaxation time, both longitudinal and transverse, of protein molecules at the amide I band and in the far-IR band. To address the problem of high differential sensitivity, the dual element detector approach and the single element approach were applied.

AB - Time-resolved infrared (IR) pump-probe experiments were conducted at FELIX, the free electron laser (FEL) at Nieuwegein, The Netherlands. The study aims to measure the relaxation time, both longitudinal and transverse, of protein molecules at the amide I band and in the far-IR band. To address the problem of high differential sensitivity, the dual element detector approach and the single element approach were applied.

UR - https://www.scopus.com/pages/publications/0032050480

UR - https://www.scopus.com/pages/publications/0032050480#tab=citedBy

U2 - 10.1016/S0168-9002(98)00077-1

DO - 10.1016/S0168-9002(98)00077-1

M3 - Conference article

AN - SCOPUS:0032050480

SN - 0168-9002

VL - 407

SP - 504

EP - 508

JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

IS - 1-3

Y2 - 18 August 1997 through 22 August 1997

ER -

Picosecond IR dynamics: Lessons learned

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this