Physiological role of stalk lengthening in caulobacter crescentus

Eric A. Klein, Susan Schlimpert, Velocity Hughes, Yves V. Brun, Martin Thanbichler, Zemer Gitai

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

The Gram-negative bacterium Caulobacter crescentus forms a thin polar stalk, which mediates its attachment to solid surfaces. Whereas stalks remain short (1 μm) in nutrient-rich conditions, they lengthen dramatically (up to 30 μm) upon phosphate starvation. A long-standing hypothesis is that the Caulobacter stalk functions as a nutrient scavenging "antenna" that facilitates phosphate uptake and transport to the cell body. The mechanistic details of this model must be revisited, given our recent identification of a protein-mediated diffusion barrier, which prevents the exchange of both membrane and soluble proteins between the stalk extension and the cell body. In this report, we discuss the potential of stalks to facilitate nutrient uptake and propose additional physiological roles for stalk elongation in Caulobacter cells.

Original languageEnglish (US)
Article numbere24561
JournalCommunicative and Integrative Biology
Volume6
Issue number4
DOIs
StatePublished - 2013

All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences(all)

Keywords

  • Compartmentalization
  • Diffusion barrier
  • Fitness
  • Morphological adaptation
  • Phosphate scavenging
  • Stalk

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