Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping

Richard S. Galos; Jim Williams; Tom Shenk; Nicholas Jones

doi:10.1016/0042-6822(80)90356-6

Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping

Richard S. Galos, Jim Williams, Tom Shenk, Nicholas Jones

Molecular Biology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Sites of host-range mutations have been mapped physically on the adenoviral genome by both recombinational mapping with host-range deletion mutants and by marker rescue. The results from the two methods are in excellent agreement; one group of mutations is assigned to the sequence between 1.3 and 3.7 units and the other set to the sequence between 6.1 and 8.5 units.

Original language	English (US)
Pages (from-to)	510-513
Number of pages	4
Journal	Virology
Volume	104
Issue number	2
DOIs	https://doi.org/10.1016/0042-6822(80)90356-6
State	Published - 1980

All Science Journal Classification (ASJC) codes

Virology

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10.1016/0042-6822(80)90356-6

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title = "Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping",

abstract = "Sites of host-range mutations have been mapped physically on the adenoviral genome by both recombinational mapping with host-range deletion mutants and by marker rescue. The results from the two methods are in excellent agreement; one group of mutations is assigned to the sequence between 1.3 and 3.7 units and the other set to the sequence between 6.1 and 8.5 units.",

author = "Galos, \{Richard S.\} and Jim Williams and Tom Shenk and Nicholas Jones",

note = "Funding Information: We thank Merlyn Williams for valuable technical assistance. This work was supported by a research grant to J.W. from the National Cancer Institute, and a grant from the American Cancer Society to T.S.",

year = "1980",

doi = "10.1016/0042-6822(80)90356-6",

language = "English (US)",

volume = "104",

pages = "510--513",

journal = "Virology",

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publisher = "Academic Press Inc.",

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T1 - Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping

AU - Galos, Richard S.

AU - Williams, Jim

AU - Shenk, Tom

AU - Jones, Nicholas

N1 - Funding Information: We thank Merlyn Williams for valuable technical assistance. This work was supported by a research grant to J.W. from the National Cancer Institute, and a grant from the American Cancer Society to T.S.

PY - 1980

Y1 - 1980

N2 - Sites of host-range mutations have been mapped physically on the adenoviral genome by both recombinational mapping with host-range deletion mutants and by marker rescue. The results from the two methods are in excellent agreement; one group of mutations is assigned to the sequence between 1.3 and 3.7 units and the other set to the sequence between 6.1 and 8.5 units.

AB - Sites of host-range mutations have been mapped physically on the adenoviral genome by both recombinational mapping with host-range deletion mutants and by marker rescue. The results from the two methods are in excellent agreement; one group of mutations is assigned to the sequence between 1.3 and 3.7 units and the other set to the sequence between 6.1 and 8.5 units.

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U2 - 10.1016/0042-6822(80)90356-6

DO - 10.1016/0042-6822(80)90356-6

M3 - Article

C2 - 6994340

AN - SCOPUS:0018829052

SN - 0042-6822

VL - 104

SP - 510

EP - 513

JO - Virology

JF - Virology

IS - 2

ER -

Physical location of host-range mutations of adenovirus type 5; deletion and marker-rescue mapping

Abstract

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