Pharmacology and reflex responsiveness of the heart in the giant garden slug, Limax maximus

Alexander R. MacKay, Alan Gelperin

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

1. 1. The anatomy and innervation of the heart in the slug Limax maximus are described. 2. 2. The heart is myogenic and is reflexively modulated by tactile stimulation of the body surface. 3. 3. Pharmacological data suggest that cardioexcitation is serotoninergic and cardioinhibition cholinergic, although both ACh and 5-HT have biphasic effects depending on concentration. 4. 4. Cardioexcitatory and cardioinhibitory areas of the visceral ganglion were identified and modulation of heart rate by single cells demonstrated.

Original languageEnglish (US)
Pages (from-to)877-896
Number of pages20
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume43
Issue number4
DOIs
StatePublished - Dec 1 1972

All Science Journal Classification (ASJC) codes

  • Physiology

Keywords

  • Limax maximus
  • Slug heart
  • acetylcholine
  • pharmacology of slug heart
  • serotonin

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