TY - JOUR
T1 - Persistent neural activity
T2 - Prevalence and mechanisms
AU - Major, Guy
AU - Tank, David
PY - 2004/12
Y1 - 2004/12
N2 - Persistent neural activity refers to a sustained change in action potential discharge that long outlasts a stimulus. It is found in a diverse set of brain regions and organisms and several in vitro systems, suggesting that it can be considered a universal form of circuit dynamics that can be used as a mechanism for short-term storage and accumulation of sensory or motor information. Both single cell and network mechanisms are likely to co-operate in generating persistent activity in many brain areas.
AB - Persistent neural activity refers to a sustained change in action potential discharge that long outlasts a stimulus. It is found in a diverse set of brain regions and organisms and several in vitro systems, suggesting that it can be considered a universal form of circuit dynamics that can be used as a mechanism for short-term storage and accumulation of sensory or motor information. Both single cell and network mechanisms are likely to co-operate in generating persistent activity in many brain areas.
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U2 - 10.1016/j.conb.2004.10.017
DO - 10.1016/j.conb.2004.10.017
M3 - Review article
C2 - 15582368
AN - SCOPUS:9644274259
SN - 0959-4388
VL - 14
SP - 675
EP - 684
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
IS - 6
ER -