Particle/fluid interface replication as a means of producing topographically patterned polydimethylsiloxane surfaces for deposition of lipid bilayers

Anand Bala Subramaniam, Sigolene Lecuyer, Kumaran S. Ramamurthi, Richard Losick, Howard A. Stone

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

A simple method to produce topographically patterned substrates from polydimethylsiloxane (PDMS) is presented. Surfaces with positively or negatively curved features, a combination of positively and negatively curved features or geometrically complex biomimetic features are fabricated. High-quality lipid bilayers that conform to the topography of the substrates can be prepared, a characteristic useful for biophysical studies. (Figure Presented)

Original languageEnglish (US)
Pages (from-to)2142-2147
Number of pages6
JournalAdvanced Materials
Volume22
Issue number19
DOIs
StatePublished - May 18 2010

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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