Particle/fluid interface replication as a means of producing topographically patterned polydimethylsiloxane surfaces for deposition of lipid bilayers

Anand Bala Subramaniam; Sigolene Lecuyer; Kumaran S. Ramamurthi; Richard Losick; Howard A. Stone

doi:10.1002/adma.200903625

Particle/fluid interface replication as a means of producing topographically patterned polydimethylsiloxane surfaces for deposition of lipid bilayers

Anand Bala Subramaniam, Sigolene Lecuyer, Kumaran S. Ramamurthi, Richard Losick, Howard A. Stone

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

A simple method to produce topographically patterned substrates from polydimethylsiloxane (PDMS) is presented. Surfaces with positively or negatively curved features, a combination of positively and negatively curved features or geometrically complex biomimetic features are fabricated. High-quality lipid bilayers that conform to the topography of the substrates can be prepared, a characteristic useful for biophysical studies. (Figure Presented)

Original language	English (US)
Pages (from-to)	2142-2147
Number of pages	6
Journal	Advanced Materials
Volume	22
Issue number	19
DOIs	https://doi.org/10.1002/adma.200903625
State	Published - May 18 2010

All Science Journal Classification (ASJC) codes

Mechanics of Materials
Mechanical Engineering
General Materials Science

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10.1002/adma.200903625

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abstract = "A simple method to produce topographically patterned substrates from polydimethylsiloxane (PDMS) is presented. Surfaces with positively or negatively curved features, a combination of positively and negatively curved features or geometrically complex biomimetic features are fabricated. High-quality lipid bilayers that conform to the topography of the substrates can be prepared, a characteristic useful for biophysical studies. (Figure Presented)",

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AU - Subramaniam, Anand Bala

AU - Lecuyer, Sigolene

AU - Ramamurthi, Kumaran S.

AU - Losick, Richard

AU - Stone, Howard A.

PY - 2010/5/18

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AB - A simple method to produce topographically patterned substrates from polydimethylsiloxane (PDMS) is presented. Surfaces with positively or negatively curved features, a combination of positively and negatively curved features or geometrically complex biomimetic features are fabricated. High-quality lipid bilayers that conform to the topography of the substrates can be prepared, a characteristic useful for biophysical studies. (Figure Presented)

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Particle/fluid interface replication as a means of producing topographically patterned polydimethylsiloxane surfaces for deposition of lipid bilayers

Abstract

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