Palladium-catalyzed hydrostannylations of highly hindered acetylenes in hexane

M. F. Semmelhack, Richard J. Hooley

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Hexane is particularly favorable as a solvent for hydrostannylation of hindered internal alkynes by minimizing the competing formation of H2 and Bu3SnSnBu3. The optimum conditions involve Pd(OAc)2 and a donor monophosphine (PCy3) in hexane at 23°C.

Original languageEnglish (US)
Pages (from-to)5737-5739
Number of pages3
JournalTetrahedron Letters
Issue number30
StatePublished - Jul 21 2003

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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