Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling

Christopher C. Nawrat; Christopher R. Jamison; Yuriy Slutskyy; David W.C. MacMillan; Larry E. Overman

doi:10.1021/jacs.5b07678

Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling

Christopher C. Nawrat
, Christopher R. Jamison
, Yuriy Slutskyy
, David W.C. MacMillan
, Larry E. Overman

Research output: Contribution to journal › Article › peer-review

358 Scopus citations

Abstract

Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient alkenes is achieved.

Original language	English (US)
Pages (from-to)	11270-11273
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	137
Issue number	35
DOIs	https://doi.org/10.1021/jacs.5b07678
State	Published - Sep 9 2015

All Science Journal Classification (ASJC) codes

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/jacs.5b07678

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title = "Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling",

abstract = "Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient alkenes is achieved.",

author = "Nawrat, \{Christopher C.\} and Jamison, \{Christopher R.\} and Yuriy Slutskyy and MacMillan, \{David W.C.\} and Overman, \{Larry E.\}",

note = "Publisher Copyright: {\textcopyright} 2015 American Chemical Society.",

year = "2015",

month = sep,

day = "9",

doi = "10.1021/jacs.5b07678",

language = "English (US)",

volume = "137",

pages = "11270--11273",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

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}

Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling. / Nawrat, Christopher C.; Jamison, Christopher R.; Slutskyy, Yuriy et al.
In: Journal of the American Chemical Society, Vol. 137, No. 35, 09.09.2015, p. 11270-11273.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis

T2 - Formation of Quaternary Centers by Redox-Neutral Fragment Coupling

AU - Nawrat, Christopher C.

AU - Jamison, Christopher R.

AU - Slutskyy, Yuriy

AU - MacMillan, David W.C.

AU - Overman, Larry E.

PY - 2015/9/9

Y1 - 2015/9/9

N2 - Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient alkenes is achieved.

AB - Alkyl oxalates are new bench-stable alcohol-activating groups for radical generation under visible light photoredox conditions. Using these precursors, the first net redox-neutral coupling of tertiary and secondary alcohols with electron-deficient alkenes is achieved.

UR - https://www.scopus.com/pages/publications/84941249106

UR - https://www.scopus.com/pages/publications/84941249106#tab=citedBy

U2 - 10.1021/jacs.5b07678

DO - 10.1021/jacs.5b07678

M3 - Article

C2 - 26322524

AN - SCOPUS:84941249106

SN - 0002-7863

VL - 137

SP - 11270

EP - 11273

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 35

ER -

Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling

Abstract

All Science Journal Classification (ASJC) codes

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