Osmotic regulation of seamless tube growth

Jodi Schottenfeld-Roames, Amin S. Ghabrial

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Most organs are composed of tubes of differing cellular architectures, including intracellular 'seamless' tubes. Two studies examining the morphogenesis of the seamless tubes formed by the excretory canal cell in Caenorhabditis elegans reveal a previously unappreciated role for osmoregulation of tubulogenesis: hyperosmotic shock recruits canalicular vesicles to the lumenal membrane to promote seamless tube growth.

Original languageEnglish (US)
Pages (from-to)137-139
Number of pages3
JournalNature cell biology
Issue number2
StatePublished - Feb 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cell Biology


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